04 December 2023
: Case report 
A Case Report of a Rare ER+, PR- Pure Metaplastic Breast Squamous Cell Carcinoma with HER2 Overexpression
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease
Shafawati Akmal Adam1ABCDEF, Khairatul Nainey Kamaruddin1E, Nordashima Abd Shukor2BCDEF, Shahrun Niza Abdullah Suhaimi3CDE, Fuad Ismail4CDE, Mazapuspavina Md Yasin
1ABCDEF*
DOI: 10.12659/AJCR.941448
Am J Case Rep 2023; 24:e941448
Figure 2. (A, B) Immunohistochemistry (IHC) of the cyst wall curettage. (A) IHC shows that malignant cells are positive for estrogen receptors with 40% positivity of moderate to strong intensity. (B) IHC shows strong expression (3+) for erythroblastic oncogene B-2 (c-erb-B2). (400× magnification) Progesterone receptor: negative.