Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

04 December 2023 : Case report  Malaysia

A Case Report of a Rare ER+, PR- Pure Metaplastic Breast Squamous Cell Carcinoma with HER2 Overexpression

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease

Shafawati Akmal Adam1ABCDEF, Khairatul Nainey Kamaruddin1E, Nordashima Abd Shukor2BCDEF, Shahrun Niza Abdullah Suhaimi3CDE, Fuad Ismail4CDE, Mazapuspavina Md Yasin ORCID logo1ABCDEF*

DOI: 10.12659/AJCR.941448

Am J Case Rep 2023; 24:e941448

Figure 3. (A) Right breast mammogram. (B) Ultrasound of the right breast. (C) Ultrasound of the right axillary lymph node. (A) Right breast mammogram showing heterogenous fibro glandular density. The Breast imaging reporting and data system (BIRADS) level was C, showing a large mass at the right upper quadrant. Multiple smaller high-density lesions in the right upper quadrant of the breast are visible. An area of hyperdensity over the right breast, upper quadrant, is visible. The red arrows show a dense, microlobulated cystic mass (these are typical mammography findings prompting suspicion of breast cancer). There is an associated right breast diffuse opacity due to edema. No suspicious grouped microcalcifications were seen. (B) Large thick-walled lobulated cystic mass with septations occupying the right upper quadrant, measuring 2.7×3.4×3.4 cm. There was a linear hypoechogenicity across the anterior aspect of the lesion in keeping with the previous wound. Several ill-defined hypoechoic lesions at the medial aspect of the above-mentioned lesions were visible. They were increased in size and number compared with recent sonograms, at the 12 o’clock and 1 o’clock positions; ranging from 0.7 cm to 2.3 cm. The overlying skin appeared to be thickened. (C) Enlarged right axillary node with cystic area measuring 1.2 cm in short axis diameter.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923