09 November 2023
: Case report 
Exacerbation of Minimal Change Disease Following mRNA COVID-19 Vaccination
Unusual clinical course, Challenging differential diagnosis, Rare coexistence of disease or pathology
Afshin Pirzadeh1ABE, Sina Emami1AE, Jonathan E. Zuckerman2E, Niloofar Nobakht1E*DOI: 10.12659/AJCR.941621
Am J Case Rep 2023; 24:e941621
Figure 1. Kidney biopsy findings. (A) Light micrograph demonstrating unremarkable glomerulus (periodic acid Schiff stain; 400×). (B) Immunofluorescence stain for anti-human IgG demonstrating fine granular podocyte cytoplasmic “dusting” with IgG (arrows) (400×; contrast enhanced from original image for enhanced visualization of weak deposits). (C) Electron micrograph demonstrating a representative glomerular capillary loop with extensive podocyte foot process effacement (arrows). (D) Immunofluorescence stain for anti-human IgA demonstrating segmental weak granular mesangial IgA deposition (400×). (E) Electron micrograph of a mesangial region demonstrating a rare mesangial electron-dense deposit (arrow).