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14 November 2023: Articles

Immune Checkpoint Inhibitor-Induced Pure Red Cell Aplasia: A Review of 2 Cases in Metastatic Melanoma

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons

Libardo Rueda Prada A* , Tatjana Gavrancic A , Miguel O. Cadena Sanabria D , Igor Dumic C , Kirk Bourgeois B , Rebecca L. King B , Yiyi Yan D

DOI: 10.12659/AJCR.941789

Am J Case Rep 2023; 24:e941789

Figure 2. (A) Bone marrow aspirate and (B) core biopsy show hypercellular bone marrow with markedly decreased and left shifted erythropoiesis. Only rare scattered pronormoblasts were identified on the aspirate, and the biopsy showed inconspicuous erythroid islands with virtually no maturation. There was background megakaryocytic and granulocytic hyperplasia. (A) Wright Giemsa, 600× oil. (B) Hematoxylin and eosin, 200×.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923