30 January 2024
: Case report
Uncovering Primary Extranodal Diffuse Large B Cell Lymphoma in the Adrenal and Thyroid Glands
Unusual clinical course, Challenging differential diagnosis, Rare disease
Judy Li
DOI: 10.12659/AJCR.942659
Am J Case Rep 2024; 25:e942659
Figure 5. Case 2 histopathological features and immunohistochemical profile of resected thyroid specimen. (A) Diffuse infiltrate of intermediate to large cells with vesicular chromatin, prominent nucleoli and irregular nuclear contours (arrows) (hematoxylin and eosin; 40×). Immunohistochemistry demonstrated atypical cells positive for (B) CD20 (40×), (C) BCL-6 (>30%) (40×), with a (D) Ki-67 proliferation index of approximately 80% (40×).