02 April 2024
: Case report
Hemorrhagic Presentation in Primary Central Nervous System Lymphoma: A Case Study
Unusual clinical course, Challenging differential diagnosis
Filipa Marques Rodrigues1ABCDEF*, Mariana Santos2BCDF, Ricardo Martins2DFDOI: 10.12659/AJCR.942951
Am J Case Rep 2024; 25:e942951
Figure 2. 1.5 T MRI. A–C: Axial MRI T2-weighted images (A) and FLAIR images (B) showing a low-signal mass on the left basal ganglia (arrows), with associated isointensity (C) on T1-weighted images. D: This lesion revealed high signal on DWI (D1) with a corresponding low signal on the ADC map (D2), consistent with restricted diffusion (arrows). E–G: On post-contrast T1-weighted images (E), there was a homogenous enhancement of the lesion (arrow). Axial T2* images (F) depicted the hemorrhagic component, represented by marked hyposignal (arrow). No significant rCBV alterations were noted (G). Altogether, these findings were suggestive of lymphoma with associated hemorrhage. MRI – magnetic resonance imaging; FLAIR – fluid-attenuated inversion recovery; DWI – diffusion-weighted imaging; ADC – apparent diffusion coefficient; rCBV – relative cerebral blood volume.