26 February 2024
: Case report
Treatment of Medication-Related Osteonecrosis of the Jaws without Segmental Resections: A Case Series
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Tito Lúcio Fernandes


DOI: 10.12659/AJCR.942980
Am J Case Rep 2024; 25:e942980
Figure 5. Representative images of case 8. (A, B) Computed tomography (CT) scans showing osteonecrosis in the lingual region of the mandibular symphysis, and (C) pathological fracture in the left mandibular body (arrows). (D, E) CT scans after 18 months of treatment with pentoxifylline and tocopherol showing partial bone repair of the lingual region of the mandibular symphysis, and (F) spontaneous repair of the pathological fracture in the left mandibular body (arrows). (G, H) 3-month postoperative CT scans showing the result of surgery, and (I) complete spontaneous repair of the pathological fracture in the left mandibular body (arrows). (J, K) Intraoperative views of sequestrectomy and marginal mandibular resection with piezosurgery (arrows). (L) Bone sequestrations removed from the lingual region of the mandibular symphysis.