04 December 2024
: Case report 
Late Recurrence of C3 Glomerulopathy After SARS-CoV-2 Infection in a Long-Term Kidney Transplant Recipient: A Case Report
Rare disease
Giulia Bartoli ABCDEF 1, Andrea Dello Strologo F 1, Maria Arena
F 2, Egidio Galeandro AEF 1, Martina Ferro F 1, Francesca Diomedi-Camassei BCD 3, Francesco Pesce AEF 4, Giuseppe Grandaliano ADEF 1,2*
DOI: 10.12659/AJCR.944208
Am J Case Rep 2024; 25:e944208
Figure 2. Kidney transplant biopsy. (A) Light microscopy: membranoproliferative changes, lobulation of the glomerulus; moderate absorption of the capillary wall; obliteration of the capillary lumens; and variable increase in the mesangial matrix. Tubulointerstitium: moderate tubular atrophy; interstitial fibrosis; modest inflammatory infiltrate. (B) Electron microscopy (EM): subendothelial deposits. (C) Immunofluorescence microscopy: C4d++ peritubular and glomerural capillaries. (D) Immunofluorescence microscopy: C3++, Lambda (L)+, Kappa (K)-, C1q -, IgG-, IgA -.