14 July 2024
: Case report
Destructive Cryptococcal Osteomyelitis Mimicking Tuberculous Spondylitis
Mistake in diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Yifan Zhou1BCDEF, Xiaoli Huang1BCDE, Yufei Liu1F, Yuanhong Zhou1A, Xiaolin Zhou1A, Qiang LiuDOI: 10.12659/AJCR.944291
Am J Case Rep 2024; 25:e944291
Figure 5. Computed tomography-guided needle biopsy for lesion at thoracic T10 vertebrae with staining method. (A) Hematoxylin and eosin stain reveals the granulomatous inflammation with histiocytes, multinucleated giant cells and leukomonocyte. (B) Acid-fast staining reveals acid-fast negative yeast cells. (C) Mucicarmine silver stain shows yeast-like organisms with a thick mucinous wall as highlighted (arrow). (D) Periodic acid-Schiff (PAS) stain reveals several 10 μm diameter PAS-positive spherules with prominent capsules. Magnification ×400.






