05 October 2024
: Case report
Concurrent Diagnosis of Chronic Lymphocytic Leukemia and Plasma Cell Myeloma: Report of 2 Cases and Differential Diagnostic Considerations
Challenging differential diagnosis, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Oluwole Odujoko1ABCDEF*, Shubhneet Bal1BF, Neil Kansal2EF, Nusrat F. Pathan1EF, Gunjan Gupta1ABEFDOI: 10.12659/AJCR.944707
Am J Case Rep 2024; 25:e944707
Figure 1. Sections show bone marrow aspirate and biopsy with increased plasma cells (A, Wright Giemsa, 100×; B, H&E, 10×). These plasma cells account for 10–15% of marrow cellularity (C, IHC, CD138 stain, 10×) and also aberrantly express cyclin D1 (D, IHC, 10×). Increased CD20+ B cells with a few ill-defined clusters (E, IHC, 10×) and rare scattered CD3+ T cells (F, IHC, 10×). H&E – hematoxylin and eosin; IHC – immunohistochemistry.