05 October 2024
: Case report
Concurrent Diagnosis of Chronic Lymphocytic Leukemia and Plasma Cell Myeloma: Report of 2 Cases and Differential Diagnostic Considerations
Challenging differential diagnosis, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Oluwole Odujoko1ABCDEF*, Shubhneet Bal1BF, Neil Kansal2EF, Nusrat F. Pathan1EF, Gunjan Gupta1ABEFDOI: 10.12659/AJCR.944707
Am J Case Rep 2024; 25:e944707
Figure 2. Flow cytometry analysis of bone marrow aspirate shows CLL. CD5+/CD19+ B lymphocytes (upper outer quadrant, 8.02%, blue arrow) (A). CD19+ B lymphocytes aberrantly expressing CD23 (upper outer quadrant, 7.92%, blue arrow) (B). CD5+ B cells with aberrant expression of CD23 (upper outer quadrant, 8.12%, blue arrow) (C). In (A), lower outer quadrant shows CD5+/CD19- T cells. There is a separate population of CD38+ bright plasma cells plotted against forward scatter (blue arrow, 8.03%) (D). This population of plasma cells shows kappa light chain restriction (E, F).