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05 October 2024 : Case report  USA

Concurrent Diagnosis of Chronic Lymphocytic Leukemia and Plasma Cell Myeloma: Report of 2 Cases and Differential Diagnostic Considerations

Challenging differential diagnosis, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology

Oluwole Odujoko1ABCDEF*, Shubhneet Bal1BF, Neil Kansal2EF, Nusrat F. Pathan1EF, Gunjan Gupta1ABEF

DOI: 10.12659/AJCR.944707

Am J Case Rep 2024; 25:e944707

Figure 2. Flow cytometry analysis of bone marrow aspirate shows CLL. CD5+/CD19+ B lymphocytes (upper outer quadrant, 8.02%, blue arrow) (A). CD19+ B lymphocytes aberrantly expressing CD23 (upper outer quadrant, 7.92%, blue arrow) (B). CD5+ B cells with aberrant expression of CD23 (upper outer quadrant, 8.12%, blue arrow) (C). In (A), lower outer quadrant shows CD5+/CD19- T cells. There is a separate population of CD38+ bright plasma cells plotted against forward scatter (blue arrow, 8.03%) (D). This population of plasma cells shows kappa light chain restriction (E, F).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923