21 December 2024
: Case report 
Hydroxychloroquine as a Promising Therapy for Systemic IgG4-Related Disease: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease
Rienke Fijn AE 1*, Nicky Janssens ABEF 1, Evelien Bodar DE 1, Marianne Marloes Nagtegaal DE 2, Faiz Karim DE 1DOI: 10.12659/AJCR.944731
Am J Case Rep 2024; 25:e944731
Figure 3. Histology of the salivary gland. (A) H&E staining showing lymphocytes, plasma cells, and storiform fibrosis. (B) Immunohistochemical staining for IgG-positive plasma cells revealing widely scattered IgG plasma cells with an average of 653 per HPF out of 3 HPF. (C) Immunohistochemical staining for IgG4 showing IgG4-positive plasma cells with an average of 417 per HPF out of 3 HPF with a ratio of 0.6 to total IgG plasma cells in the tissue. This figure is at 200× magnification. H&E – haematoxylin and eosin; HPF – high-power field.