10 January 2025
: Case report 
Pregnancy Complicated by Rapidly Progressing Vulvar Melanoma: A Case Study
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease
Bagas Satriyo Wicaksono
1ABEF*, Aditiyono Aditiyono 2ABD, Dina Marlina 1ABEF, Aditya Utomo 1ABEF, Putri Nadhira Adinda Adriansyah 3BEF, Dody Novrial 4BCD
DOI: 10.12659/AJCR.944972
Am J Case Rep 2025; 26:e944972
Figure 2. Biopsy specimen of the patient. (A) Biopsy result in 2020, malignant tumor cells appear solid and diffuse (black arrows), areas of necrosis and hemorrhage are visible (red arrows), magnification ×200. (B) Biopsy result in 2021, Polymorphic atypical tumor cells appear solid and diffusely arranged, some containing brown pigment (black arrow), mitotic activity is relatively high (red arrow), magnification ×400. (C) Biopsy result in 2022, invasion of pigmented malignant tumor cells is seen in the cervical connective tissue stroma (black arrow), and tumor embolism is visible in the lymphovascular space (red arrow), magnification ×200.