08 January 2025
: Case report 
Radiological and Pathological Analysis of Pembrolizumab-Associated Lung Lesions: Diagnostic Challenges and Management
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons
Tomohito Okano BDEF 1, Hajime Fujimoto ABC 1, Toshiyuki Ito BDE 1, Atsushi Tomaru BDE 1, Haruko Saiki BDE 1, Tatsuki Tsuruga ABE 1, Taro Yasuma BCD 2,3, Corina N. D'Alessandro-Gabazza CDE 2,3, Esteban C. Gabazza
DF 1,2,3*, Tetsu Kobayashi ABDE 1,3
DOI: 10.12659/AJCR.945022
Am J Case Rep 2025; 26:e945022
Figure 2. Lung CT scan findings. CT scans of the lungs, conducted with an axial slice thickness of 0.5 mm, were obtained before the initiation of the 31st course of pembrolizumab treatment. These scans revealed multiple infiltrating nodular shadows of varying sizes and some areas of ground-glass opacity, distributed bilaterally across the lung fields (A–D). A specific nodule, highlighted by a circled area, was selected for biopsy during the subsequent bronchoscopic procedure (D). CT, computed tomography.