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08 January 2025 : Case report  Japan

Radiological and Pathological Analysis of Pembrolizumab-Associated Lung Lesions: Diagnostic Challenges and Management

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons

Tomohito Okano1BDEF, Hajime Fujimoto1ABC, Toshiyuki Ito1BDE, Atsushi Tomaru1BDE, Haruko Saiki1BDE, Tatsuki Tsuruga1ABE, Taro Yasuma23BCD, Corina N. D'Alessandro-Gabazza23CDE, Esteban C. Gabazza ORCID logo123DF*, Tetsu Kobayashi ORCID logo13ABDE

DOI: 10.12659/AJCR.945022

Am J Case Rep 2025; 26:e945022

Figure 3. Bronchoscopic findings. A bronchoscopic examination was conducted prior to the 31st course of pembrolizumab treatment. The bronchoscopic examination provided detailed images of the tracheal bifurcation (A), the bifurcation of the right upper and lower lobe bronchi (B), the right middle bronchus (C), and the segmental bronchi of the right lower lobe (B9 and B10) (D). Additionally, an endobronchial ultrasound (EBUS) was used to guide the biopsy of a nodule located in the right lower lobe (E), ensuring precise localization and sampling of the lesion.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923