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08 January 2025 : Case report  Japan

Radiological and Pathological Analysis of Pembrolizumab-Associated Lung Lesions: Diagnostic Challenges and Management

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons

Tomohito Okano1BDEF, Hajime Fujimoto1ABC, Toshiyuki Ito1BDE, Atsushi Tomaru1BDE, Haruko Saiki1BDE, Tatsuki Tsuruga1ABE, Taro Yasuma23BCD, Corina N. D'Alessandro-Gabazza23CDE, Esteban C. Gabazza ORCID logo123DF*, Tetsu Kobayashi ORCID logo13ABDE

DOI: 10.12659/AJCR.945022

Am J Case Rep 2025; 26:e945022

Figure 5. Clinical course following treatment of lung injury. This figure presents serial CT scans alongside the clinical course of the patient. Day 1 corresponds to the initial patient visit. Day 46 presents data from a drug-free follow-up, providing insights into the patient’s condition without therapeutic intervention. Day 66 reflects data collected after the first course of steroid pulse therapy, highlighting the immediate therapeutic impact. Day 194 shows the patient’s status post-completion of prednisone therapy, offering a longer-term perspective on treatment efficacy. The CT scans were performed with an axial slice thickness of 0.5 mm. CT, computed tomography.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923