18 April 2025
: Case report 
Diagnostic and Surgical Management of Nesidioblastosis in a 42-Year-Old Man with Refractory Hypoglycemia
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Cleomar Ana de Souza Valentim
AEF 1, Vivien Suemi Arimura AEF 2, Isabella De Melo Pompei AEF 2, Denis Bonvechio BDF 3, Marcio Shimabuku Silva BDF 3, Fabio José Turrini BEF 3, Mariana Soares Dalla Mariga Jorgino AEF 4, Andre Silva Valentim ABCDEFG 4*
DOI: 10.12659/AJCR.945453
Am J Case Rep 2025; 26:e945453
Figure 3. Anatomopathological/immunohistochemical examination. Photomicrographs of the pancreas: 400×, hematoxylin and eosin staining. (A) Large, irregular islet; (B) Islet near ductule (ductuloinsular complex); (C) Large neuroendocrine cell; (D) Islet confluence (synaptophysin); (E) Large neuroendocrine cell showing insulin positivity.