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22 February 2025 : Case report  China

Rare Presentation of Middle Ear Neuroendocrine Tumor: A Case Report

Unknown etiology, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Patient complains / malpractice, Unexpected drug reaction, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Nan Zeng ABCD 1, Qiong Yang ABCD 1, Jing Hu ABG 1, Shang Yan EF 2*

DOI: 10.12659/AJCR.945602

Am J Case Rep 2025; 26:e945602

Figure 4. (A) HE Staining: Fibrous connective tissue contains irregularly arranged cell nests, forming glandular or solid structures. The cell nuclei are hyperchromatic with fine chromatin. Mitotic figures are rare. No necrosis is observed. (B) Immunohistochemical examination: synaptophysin shows diffuse positive staining. (C) Immunohistochemical txamination: Ki67 shows approximately 2% positivity.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923