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30 December 2024 : Case report  Japan

B-Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma Mimicking Fibrosing Mediastinitis: A Case Report and Diagnostic Insight

Unknown etiology, Challenging differential diagnosis, Unusual or unexpected effect of treatment

Aya Kitamura ABCDEF 1, Shigehisa Yanagi ABCDEFG 1*, Kotaro Shide ORCID logo ABCDEF 2, Yuichiro Sato ABCDE 3, Ayako Kamiunten BDE 2, Yasuhiro Yamanari BE 1, Akiko Kitamura E 1, Makoto Sumiyoshi E 1, Yasuharu Oda ORCID logo E 1, Hironobu Tsubouchi E 1, Kazuya Shimoda ADEF 2, Taiga Miyazaki ADEF 1

DOI: 10.12659/AJCR.945804

Am J Case Rep 2024; 25:e945804

Figure 3. Thoracic biopsy findings of the mediastinal mass-like lesion. The specimen comprised an undemarcated dense fibrotic lesion (A, B). There was mild infiltration of small- to medium-sized lymphocytes. (C–F) Immunohistochemical findings. The infiltrating lymphocytes were composed of CD3-positive T lymphocytes and CD20-positive B lymphocytes (C, D). No apparent neoplastic proliferations of cytokeratin AE1/AE3-positive cells or terminal deoxynucleotidyl transferase (TdT)-positive cells was detected (E, F). A: 12.5×, B: 200×, C–F: 40× magnification. A, B: Hematoxylin and eosin (H&E) stain.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923