Multiple Myeloma Presenting as Breast Metastasis: Diagnostic Challenges and Case Analysis

Gloria Messina; Maria Antonia Fucile; Marianne Kupper; Marco Campitiello; Francesca Plastino; Pierre-Olivier Legros; Julie Egea; Philippe Carassou; Giampaolo Tortora; Raffaele Longo

doi:10.12659/AJCR.945853

24 April 2025 : Case report Italy

Multiple Myeloma Presenting as Breast Metastasis: Diagnostic Challenges and Case Analysis

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Gloria Messina^1ABCDEF, Maria Antonia Fucile^1ABCDEF, Marianne Kupper^2ABDE, Marco Campitiello^2ADEF, Francesca Plastino^2AF, Pierre-Olivier Legros^2ABF, Julie Egea

^2ABEF, Philippe Carassou^3ABDEF, Giampaolo Tortora^1ADEF, Raffaele Longo^2ABCDEF*

DOI: 10.12659/AJCR.945853

Am J Case Rep 2025; 26:e945853

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Figure 1. (A) Bone morrow infiltration from myeloid cells (H&E stain, 400×). (B, C) Myeloma plasma cells exhibit IgA kappa (B) and are negative for IgA lambda (C) (histochemistry, 400×). H&E – hematoxylin and eosin.

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Multiple Myeloma Presenting as Breast Metastasis: Diagnostic Challenges and Case Analysis

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