24 April 2025
: Case report 
Multiple Myeloma Presenting as Breast Metastasis: Diagnostic Challenges and Case Analysis
Challenging differential diagnosis, Unusual setting of medical care, Rare disease
Gloria Messina1ABCDEF, Maria Antonia Fucile1ABCDEF, Marianne Kupper2ABDE, Marco Campitiello2ADEF, Francesca Plastino2AF, Pierre-Olivier Legros2ABF, Julie Egea
2ABEF, Philippe Carassou3ABDEF, Giampaolo Tortora1ADEF, Raffaele Longo2ABCDEF*
DOI: 10.12659/AJCR.945853
Am J Case Rep 2025; 26:e945853
Figure 2. (A) Multiple, nodular lesions in the right breast, without any axillary lymph node involvement or pathological microcalcifications. A lesion of 14 mm in diameter was located in the upper-inner quadrant and the other 3 lesions were located at the intersection of the internal quadrants of the right breast (red arrows; mammography). (B, C) Hypermetabolic lesion of the external lower (B) and the upper-inner (C) quadrant of the right breast (red arrows; 18F FDG-PET-CT scan, axial section). 18F FDG – 2-deoxy-2-[fluorine-18] fluoro-D-glucose; PET – positron emission tomography; CT – computed tomography.