Figure 4. This is a diagnostic algorithm for the accurate diagnosis of Mondor’s disease (MD). The diagnostic process begins with a patient interview to assess for chest wall pain and identify risk factors such as recent surgery trauma or excessive physical activity. A physical examination follows to check for typical findings such as a palpable cord at the pain site. If a cord is detected, ultrasound imaging is performed to confirm a hypoechoic tubular structure with absent blood flow indicative of thrombophlebitis. If findings from both the physical and ultrasound imaging are consistent with MD, treatment can be initiated. However, in the absence of typical findings, further imaging such as computed tomography (CT) may be necessary to rule out other conditions, especially malignancies that must not be overlooked.