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09 March 2025 : Case report  Japan

A 58-Year-Old Man with a History of Autoimmune Thyroiditis Diagnosed with Mucosa-Associated Lymphoid Tissue Lymphoma and Papillary Carcinoma of the Thyroid

Challenging differential diagnosis, Rare disease

Naru Babaya ORCID logo ABCDEF 1*, Sawa Yoshida ORCID logo ABCD 1, Shinsuke Noso ORCID logo D 1, Yoshihisa Hiromine ORCID logo D 1, Yasunori Taketomo ORCID logo D 1, Takayuki Kimura BD 2, Hiroaki Kakutani BD 3, Takao Satou BD 4, Hiroshi Ikegami ORCID logo DE 1, Norikazu Maeda ORCID logo DE 1

DOI: 10.12659/AJCR.946022

Am J Case Rep 2025; 26:e946022

Figure 1. Thyroid images. (A) Diffuse enlargement of the thyroid gland with hypoechoic areas and heterogeneous inner echogenicity, internal linear echogenic strands, and posterior echo enhancement; this finding is suspicious for malignant lymphoma (green arrow). (B) In the left lobe, a mass suspected of being malignant (suspect of the papillary carcinoma: yellow arrows) and measuring 17×15 mm with calcification, partially indistinct borders, and an irregular hypoechoic area can be observed. (C) Computed tomography of the neck shows a diffusely enlarged thyroid gland (yellow arrow) compressing the trachea (green arrow). (D) Positron emission tomography with 18F-fluorodeoxyglucose shows strong 18F-fluorodeoxyglucose uptake throughout the thyroid gland (green arrow), suggesting a positive signal caused by Hashimoto’s thyroiditis or malignant lymphoma.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923