17 February 2025
: Case report 
A 20-Year-Old Woman with Metachronous Polyostotic Simple (Unicameral) Bone Cysts in 9 Sites: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease
Nicole Liddy
ABDEF 1, Sten H. Kajitani F 2, John M. Gross BDE 1, Ying Zou DE 1, Brock Lindsey DE 1, Albert J. Aboulafia DE 1*
DOI: 10.12659/AJCR.946165
Am J Case Rep 2025; 26:e946165
Figure 7. Radiographs of treated lesions demonstrate obliteration of previously identified lucent lesions with marked sclerosis (A) AP radiograph of right tibia taken 7 months after open biopsy, curettage, local adjuvant with argon beam and doxycycline, and bone grafting for proximal lesion (red arrow). (B) Single-view radiograph of left humerus taken 13 months after open biopsy, curettage, local adjuvant with argon beam and doxycycline and bone grafting (yellow arrow). (C) AP radiograph of left tibia and fibula taken 13 months after open biopsy, curettage, local adjuvant with argon beam and doxycycline, and bone grafting for proximal lesion and 3 months after doxycycline sclerotherapy for distal lesion (blue arrows). (D) AP radiograph of the pelvis taken 5 months after doxycycline sclerotherapy. (E) AP radiograph of right hand taken 2 months after open biopsy, curettage, local adjuvant with argon beam and doxycycline and bone grafting demonstrates complete filling of previously identified lucent lesion. AP – anteroposterior.