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24 February 2025 : Case report  Ecuador

Severe COVID-19 Pneumonia, Opportunistic Candida krusei Infection, and Acute Respiratory Distress Syndrome with Pulmonary Arterial Hypertension Treated with Bosentan: A Case Report

Unusual clinical course, Management of emergency care

Killen H. Briones-Claudett ORCID logo123ABCDEFG*, Killen H. Briones-Zamora ORCID logo24ABCDEFG, Jaime Galo Benites Solis ORCID logo34ACDEFG, Doménica I. Huilcapi Borja ORCID logo4ABCDEFG, Karelys Nicole Arteaga Ocaña ORCID logo4ABCDEFG, Maria Antonieta Touriz Bonifaz5BCDEFG, Pedro Barberan-Torres ORCID logo1BCDEFG, Michelle Grunauer ORCID logo6BCDEFG

DOI: 10.12659/AJCR.946400

Am J Case Rep 2025; 26:e946400

Figure 2. Bronchoscopic evaluation during active COVID-19 and fungal co-infection. Sequential bronchoscopic findings revealing: (A) inflammatory changes with hemorrhagic foci in bronchial mucosa; (B) Mucosal fold hypertrophy with characteristic fungal plaques; (C) active purulent secretions in segmental airways; (D) confirmed Candida krusei colonization presenting as whitish plaques; (E) Mucosal edema with epithelial disruption; and (F) enhanced vascular patterns reflecting inflammatory response.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923