Severe COVID-19 Pneumonia, Opportunistic Candida krusei Infection, and Acute Respiratory Distress Syndrome with Pulmonary Arterial Hypertension Treated with Bosentan: A Case Report

Killen H. Briones-Claudett; Killen H. Briones-Zamora; Jaime Galo Benites Solis; Doménica I. Huilcapi Borja; Karelys Nicole Arteaga Ocaña; Maria Antonieta Touriz Bonifaz; Pedro Barberan-Torres; Michelle Grunauer

doi:10.12659/AJCR.946400

24 February 2025 : Case report Ecuador

Severe COVID-19 Pneumonia, Opportunistic Candida krusei Infection, and Acute Respiratory Distress Syndrome with Pulmonary Arterial Hypertension Treated with Bosentan: A Case Report

Unusual clinical course, Management of emergency care

Killen H. Briones-Claudett

^123ABCDEFG*, Killen H. Briones-Zamora

^24ABCDEFG, Jaime Galo Benites Solis

^34ACDEFG, Doménica I. Huilcapi Borja

^4ABCDEFG, Karelys Nicole Arteaga Ocaña

^4ABCDEFG, Maria Antonieta Touriz Bonifaz^5BCDEFG, Pedro Barberan-Torres

^1BCDEFG, Michelle Grunauer

^6BCDEFG

DOI: 10.12659/AJCR.946400

Am J Case Rep 2025; 26:e946400

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Figure 3. Temporal progression of clinical course and therapeutic interventions. Chronological documentation of disease progression, therapeutic interventions, and clinical responses in severe COVID-19 complicated by pulmonary hypertension and Candida krusei infection, highlighting key treatment milestones including bosentan initiation and antifungal therapy.

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Severe COVID-19 Pneumonia, Opportunistic Candida krusei Infection, and Acute Respiratory Distress Syndrome with Pulmonary Arterial Hypertension Treated with Bosentan: A Case Report

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