Figure 5 Histopathology of invasive ductal carcinoma (IDC) with skin ulceration: (A) 10× objective (100× total magnification) showing skin ulceration and necrosis of the epidermis (most visible on right side of the figure) associated with IDC. The figure demonstrates a disrupted epidermal layer with underlying tumor infiltration. Irregular nests and cords of malignant cells are seen invading the dermis, accompanied by a desmoplastic stromal reaction and inflammatory infiltrate. (B) 40× objective (400× total magnification) of the tumor cells, revealing key cytological features of IDC. The figure shows pleomorphic tumor cells with enlarged, hyperchromatic nuclei, prominent nucleoli, and increased mitotic activity. The cells display a loss of normal ductal architecture, forming solid nests or sheets. Cytoplasm is abundant and eosinophilic.