07 May 2025
: Case report 
Rare Coexisting Hepatocellular and Gallbladder Carcinomas: A Case Report
Challenging differential diagnosis, Rare coexistence of disease or pathology
Kristína Cmarková
EF 1, Lenka Nosakova EF 2, Miroslav Pindura DE 1*, Roman Kyčina EF 1, Juraj Marcinek BDE 3, Juraj Miklušica AE 1
DOI: 10.12659/AJCR.946739
Am J Case Rep 2025; 26:e946739
Figure 2 (A–D) Gallbladder carcinoma at various magnifications, with hematoxylin-eosin stain. Fibrohyaline thickened gallbladder wall without smooth muscle layer, typical for the terminal stage of chronic cholecystitis, the so-called “porcelain gallbladder.” The gallbladder cavity with remnants of cholelithiasis, with completely absent mucosa. Original magnification ×40 (A). The gallbladder wall is infiltrated with irregular glandular formations. Original magnification ×100. (B). Cubic and cylindrical cells with voluminous, pleomorphic, and dense nuclei, indicating adenocarcinoma of the gallbladder. Original magnification ×400 (C) and ×200 (D). (Archive of the Institute of Pathological Anatomy UHM).