07 May 2025
: Case report 
Rare Coexisting Hepatocellular and Gallbladder Carcinomas: A Case Report
Challenging differential diagnosis, Rare coexistence of disease or pathology
Kristína Cmarková
EF 1, Lenka Nosakova EF 2, Miroslav Pindura DE 1*, Roman Kyčina EF 1, Juraj Marcinek BDE 3, Juraj Miklušica AE 1
DOI: 10.12659/AJCR.946739
Am J Case Rep 2025; 26:e946739
Figure 3 (A–F) Histopathological appearance of hepatocellular carcinoma, with hematoxylin-eosin stain. Expansive tumor with an absent capsula on the surface, with extensive inflammatory peripheral reaction (A). Irregular, polygonal cells with eosinophilic cytoplasm and voluminous vesicular nuclei with visualized nucleoli. Numerous multinucleated tumor cells and rich lymphoplasmacytic inflammation in the tumor with a high concentration of neutrophils, characteristic for the “inflammatory” type of HCC (B). Original magnifications (A – ×40, B – ×100). Uniform component of hepatocellular carcinoma (C – ×200, D – ×400). Pleomorphic component of hepatocellular carcinoma (E – ×200, F – ×400). (Archive of the Institute of Pathological Anatomy UHM).