26 April 2025
: Case report 
Diagnostic and Therapeutic Challenges in an Acute Variegate Porphyric Crisis Complicated by Anuric Renal Failure and Multiorgan Dysfunction: A Case Report
Challenging differential diagnosis, Rare disease
Peter B. Conroy ABCDEF 1, Sue Davel BCDEF 2, Jacques A.J. Malherbe
BCDEF 3,4, Simon J. Carrivick BCDEF 5, Edward N. Briggs BCDEF 1*
DOI: 10.12659/AJCR.946969
Am J Case Rep 2025; 26:e946969
Figure 2. (A) Prismaflex continuous renal replacement therapy (CRRT) circuit control unit utilized for the treatment of this patient. (B) The connection of two 3-mL syringes infusing 0.9% normal saline via a plastic connector (red arrows) are shown, which bypasses the infrared blood leak detector. This enabled therapeutic plasma exchange (TPE) and CRRT to proceed without repeated activation of the blood leak detector alarm.