06 June 2025
: Case report 
Crystalline Nephropathy Due to 2,8-Dihydroxyadeninuria in a Transplanted Kidney: 2 Case Reports
Unusual clinical course, Challenging differential diagnosis
Hafiz Muhammad Ali Raza BE 1, Atif Ibrahim BE 1, Manish Talwar BDF 2, Vasanthi Balaraman
BF 2, Anshul Bhalla ABDEF 3, Barry M. Wall BE 2,4*, L. Nicholas Cossey BF 5
DOI: 10.12659/AJCR.946972
Am J Case Rep 2025; 26:e946972
Figure 1 Pigmented, intratubular DHA crystals consisting of needle-shaped crystals arranged in fan-shaped to radial arrays. The tubular epithelium shows associated tubular epithelial simplification and reactive nuclei consistent with acute tubular injury (H&E stained section, 200×).