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25 October 2025 : Case report  Brazil

Intraosseous Cellular Schwannoma in the Infraorbital Region: A Rare Case

Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Edmundo Luis Rodrigues Pereira ORCID logo BCD 1, Rebeca Viera Costa ABCDEFG 2, Jeovanna Brito de Moraes ORCID logo ACEF 3, Alessandra Arnaud Moreira ABD 2, Thayna Silva do Carmo Tavares ORCID logo ACE 2, Fabricio Passador-Santos ORCID logo BCD 4, Lucas Rodrigues Pinheiro ORCID logo CDE 5, Sérgio de Melo Alves Júnior ORCID logo ACDEF 2, João de Jesus Viana Pinheiro ORCID logo ACDEG 2*

DOI: 10.12659/AJCR.947024

Am J Case Rep 2025; 26:e947024

Figure 4 Histological images of the surgical specimen(A) Hematoxylin-eosin staining at 630× magnification showing sheets of spindle cells. Scale bar: 5 μm. (B) Hematoxylin-eosin staining at 630× magnification showing neoplastic cells arranged in sheets and bundles with a storiform pattern. Scale bar: 5 μm. (C) Immunohistochemical staining for Ki-67 shows nuclear positivity in proliferating cells (black arrowhead) at 400× magnification. Scale bar: 20 μm. (D) S-100 protein immunostaining demonstrates strong and diffuse cytoplasmic expression at 200× magnification. Scale bar: 20 μm.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923