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07 June 2025 : Case report  China

Efficacy of Hepatic Artery Infusion Chemotherapy with Bevacizumab and Sintilimab in Advanced Hepatocellular Carcinoma: A Case Report

Unusual clinical course, Unusual or unexpected effect of treatment, Educational Purpose (only if useful for a systematic review or synthesis)

Chenguang Hua E 1, Shanhe Huang C 1, Bo Ding D 1, Junru Chen B 1, Chaofeng Ding AG 1*

DOI: 10.12659/AJCR.947317

Am J Case Rep 2025; 26:e947317

Figure 3 Timeline of tumor responses and tumor biomarkers alone in the clinical course. (A) The timeline of the patient’s therapies and changes of conditions. (B) DWI, T2WI and coronal views of MRI showed consistent remission of HCC during combined therapy. The line charts show the changes of AFP and PIVKA-II. HCC – hepatocellular carcinoma; HAIC – hepatic artery infusion chemotherapy; AFP – alpha-fetoprotein; PIVKA-II – protein induced by vitamin K absence-II; SBRT – stereotactic body radiation therapy; TACE – transarterial chemoembolization; DWI – diffusion weighted imaging; T2WI – T2-weighted imaging; MRI – magnetic resonance imaging.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923