25 August 2025
: Case report 
Two Cases of Charcot-Marie-Tooth Disease Diagnosed in a 53-Year-Old Mother and a 24-Year-Old Daughter
Patient complains / malpractice, Rare disease
Junying Zhu ABDEF 1, Shimiao Dai BDE 1, Yao Li E 1, Miaomiao Ma E 1, Ming Chu DE 2, ZhiQiang Lin
DE 3, Litao Sun ABDE 1,4, Ji-Chang Zhou ABDEG 1,5*
DOI: 10.12659/AJCR.947400
Am J Case Rep 2025; 26:e947400
Figure 1 Family tree for the proband. ‘Square’ – male; ‘circle’ – female; ‘open symbol’ – unaffected carriers; ‘filled symbol’ – affected individual; ‘WT’ – wild-type allele; ‘+/−’ – heterozygous; ‘bold text’ – carrying mutation; PMP22 – peripheral myelin protein 22 gene; SH3TC2 – SH3 domain and tetratricopeptide repeats 2 gene.