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17 August 2025 : Case report  USA

Atypical Presentation of Hereditary ATTR Amyloidosis with Gastrointestinal and Hepatic Manifestations in an 88-Year-Old Woman: A Case Report

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents

Anaiya Singh ABDEF 1, Viraj Panchal ORCID logo ABDEF 2*, Shiva Jashwanth Gaddam ABDEF 3, Yousif Barzani ABDEF 4, Xiaoming Fan ABDEF 4, Kshitij Arora ABDEF 4, Rusella Mirza ABDEF 4, Terry Lairmore ABDEF 5, Poornima Ramadas ABDEF 3

DOI: 10.12659/AJCR.947690

Am J Case Rep 2025; 26:e947690

Figure 1 Histopathology of the ascending colon showing vascular and interstitial amyloid deposition where the eosinophilic amyloid deposits are prominent in vessel walls and interstitial spaces, confirmed by Congo red staining with birefringence under polarized light.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923