Atypical Presentation of Hereditary ATTR Amyloidosis with Gastrointestinal and Hepatic Manifestations in an 88-Year-Old Woman: A Case Report

Anaiya Singh; Viraj Panchal; Shiva Jashwanth Gaddam; Yousif Barzani; Xiaoming Fan; Kshitij Arora; Rusella Mirza; Terry Lairmore; Poornima Ramadas

doi:10.12659/AJCR.947690

17 August 2025 : Case report USA

Atypical Presentation of Hereditary ATTR Amyloidosis with Gastrointestinal and Hepatic Manifestations in an 88-Year-Old Woman: A Case Report

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents

Anaiya Singh^{ABDEF 1}, Viraj Panchal

^{ABDEF 2*}, Shiva Jashwanth Gaddam^{ABDEF 3}, Yousif Barzani^{ABDEF 4}, Xiaoming Fan^{ABDEF 4}, Kshitij Arora^{ABDEF 4}, Rusella Mirza^{ABDEF 4}, Terry Lairmore^{ABDEF 5}, Poornima Ramadas^{ABDEF 3}

DOI: 10.12659/AJCR.947690

Am J Case Rep 2025; 26:e947690

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Introduction Case Report Discussion Conclusions References

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Figure 3 Low-power magnification view (10×) of duodenal biopsy showing diffuse amyloid deposition visible as amorphous, eosinophilic deposits within the lamina propria and surrounding blood vessels.

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Atypical Presentation of Hereditary ATTR Amyloidosis with Gastrointestinal and Hepatic Manifestations in an 88-Year-Old Woman: A Case Report

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