19 July 2025
: Case report 
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Unusual clinical course, Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Michał J. Sekuła
ADEG 1*, Anna Jamroz-Wiśniewska ADEG 1, Urszula Chyrchel-Paszkiewicz BC 1, Aleksandra Pietruczuk BCF 1, Aleksandra Dembowska CF 1, Maciej Dubaj CDF 1, Karol Bigosiński CD 1, Konrad Rejdak AEG 1
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
Figure 2 Multiple disseminated lesions on brain MRI with morphology typical of demyelinating plaquesAxial (A–C) and sagittal (D–F) brain MRI (1.5 T) with T2 fluid-attenuated inversion recovery (A, B) and T2-weighted (D–F) sequences. The images show multiple disseminated hyperintense lesions on T2-weighted and FLAIR sequences, located in the white matter of both cerebral hemispheres, periventricularly, and in the deformed corpus callosum, with morphology typical of demyelinating plaques (yellow arrows).