19 July 2025
: Case report 
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Unusual clinical course, Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Michał J. Sekuła
ADEG 1*, Anna Jamroz-Wiśniewska ADEG 1, Urszula Chyrchel-Paszkiewicz BC 1, Aleksandra Pietruczuk BCF 1, Aleksandra Dembowska CF 1, Maciej Dubaj CDF 1, Karol Bigosiński CD 1, Konrad Rejdak AEG 1
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
Figure 4 Follow-up brain MRI demonstrating progression of the previously described lesionsAxial (A–F) and sagittal (G–H) brain MRI (1.5 T) with T2 fluid-attenuated inversion recovery (A, B), diffusion-weighted imaging (C, D) and T2 (E–H) sequences. Each series shows enlargement of lesions located in the white matter of both cerebral hemispheres, periventricularly, and in the in the deformed corpus callosum, compared to previous examination (yellow arrows). The lesion below the left lateral ventricle showing the decay features (red arrow).