An 88-Year-Old Woman with a 33-Year History of Idiopathic Portal Hypertension Presenting with Hepatocellular Carcinoma Treated with Carbon-Ion Radiotherapy

Akira Sato; Reiko Kumano; Yasushi Ariizumi; Nobuyuki Matsumoto

doi:10.12659/AJCR.947725

18 July 2025 : Case report Japan

An 88-Year-Old Woman with a 33-Year History of Idiopathic Portal Hypertension Presenting with Hepatocellular Carcinoma Treated with Carbon-Ion Radiotherapy

Rare disease

Akira Sato^{ABCDEF 1*}, Reiko Kumano^{C 2}, Yasushi Ariizumi^{C 3}, Nobuyuki Matsumoto^{A 1}

DOI: 10.12659/AJCR.947725

Am J Case Rep 2025; 26:e947725

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Figure 1 Histological features of a liver specimen obtained 26 years before the onset of hepatocellular carcinoma(A) Photomicrograph showing a rounded portal tract expanded by dense stromal fibrosis (arrow: portal vein) (Masson trichrome staining). (B) Photomicrograph showing focal dilatation of the sinusoids with poor evidence of hepatocellular inflammation in the portal region or parenchyma (hematoxylin and eosin).

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An 88-Year-Old Woman with a 33-Year History of Idiopathic Portal Hypertension Presenting with Hepatocellular Carcinoma Treated with Carbon-Ion Radiotherapy

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