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21 October 2025 : Case report  USA

High-Grade Angiosarcoma Transformation in Schwannoma and SMARCB1 Mutation: A Case Report

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Lydia Mbatidde ABCDEF 1, Rohit Sharma ABDE 2, Michael J. Michalske ABCDE 2, Jaswinder Chalia ACDE 3, Adedayo A. Onitilo ORCID logo ABCDEF 4*

DOI: 10.12659/AJCR.947742

Am J Case Rep 2025; 26:e947742

Figure 5 Epithelioid angiosarcoma arising in a schwannoma, extending to the peripheral resection margins(A) Arrows: CD31 + shows a bit of weak and granular staining around the malignant cells in areas of epithelioid angiosarcoma. (B) Arrow: Patchy positive CK (highlights epithelial or epithelioid-like cells).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923