Figure 1 MR images of nasopharyngeal carcinoma (A, B) before treatment, (C, D) after treatment. (A) T1-weighted contrast-enhanced transverse image demonstrates the tumor encircles the pituitary fossa, with bilateral encroachment upon the cavernous and carotid sinuses, anterior extension into the pterygoid sinus, meningeal breach, posterior displacement of the cerebellum and brainstem, and lateral displacement of the left temporal lobe. Rightward displacement of the brainstem was observed. (B) T1-weighted contrast-enhanced coronal image shows involvement of the middle and posterior cranial fossae, with compression of the left thalamus and brainstem, anterior displacement of the left temporal lobe, encirclement of the pituitary gland, and involvement of the first cervical vertebra and cricoid cartilage. (C, D) Post-treatment imaging demonstrated complete tumor resolution after concurrent chemoradiotherapy, with no evidence of residual infiltration in the middle or posterior cranial fossae. Treatment efficacy was classified as complete response (CR).