Refractory Pleuritis in a Patient with Silicosis, Systemic Sclerosis, and Sjögren’s Syndrome: Considering the Potential Role of Adjuvant-Induced Autoimmunity

Julia Morimoto; Yasuhito Suzuki; Ryuichi Togawa; Natsumi Watanabe; Takahiro Kumanaka; Ryutaro Tanaka; Kentaro Kazama; Koshi Saito; Rina Harigane; Ryuki Yamada; Riko Sato; Hikaru Tomita; Takashi Umeda; Mami Rikimaru; Yuki Sato; Hiroyuki Minemura; Takefumi Nikaido; Junpei Saito; Kenya Kanazawa; Xintao Wang; Yoshinori Tanino; Yoko Shibata

doi:10.12659/AJCR.947856

04 May 2025 : Case report Japan

Refractory Pleuritis in a Patient with Silicosis, Systemic Sclerosis, and Sjögren’s Syndrome: Considering the Potential Role of Adjuvant-Induced Autoimmunity

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare coexistence of disease or pathology

Julia Morimoto^{ABCDEF 1}, Yasuhito Suzuki^{ABCDEF 1*}, Ryuichi Togawa^{BDE 1}, Natsumi Watanabe^{BDE 1}, Takahiro Kumanaka^{BDE 1}, Ryutaro Tanaka^{BDE 1}, Kentaro Kazama^{BDE 1}, Koshi Saito^{BDE 1}, Rina Harigane^{BDE 1}, Ryuki Yamada^{BDE 1}, Riko Sato^{BDE 1}, Hikaru Tomita^{BDE 1}, Takashi Umeda^{BDE 1}, Mami Rikimaru^{BDE 1}, Yuki Sato^{BDE 1}, Hiroyuki Minemura^{BDE 1}, Takefumi Nikaido^{BDE 1}, Junpei Saito

^{BDEF 1}, Kenya Kanazawa

^{B 1}, Xintao Wang

^{BDE 1}, Yoshinori Tanino

^{BDE 1}, Yoko Shibata

^{ABDE 1}

DOI: 10.12659/AJCR.947856

Am J Case Rep 2025; 26:e947856

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Figure 2 Hematoxylin-eosin staining of the right lower-lobe tissue obtained by transbronchial lung cryobiopsy revealed silicotic nodules (arrows).

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Refractory Pleuritis in a Patient with Silicosis, Systemic Sclerosis, and Sjögren’s Syndrome: Considering the Potential Role of Adjuvant-Induced Autoimmunity

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