25 August 2025
: Case report 
Rapid Progression of Primary Hepatic Neuroendocrine Carcinoma: A Case Report Demonstrating Drastic Oncological Behavior
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Rare disease, Adverse events of drug therapy
Rina Kobayashi BF 1, Tomohide Hori
ABCDEF 1*, Makoto Yamawaki CDF 2, Shigeki Nakayama DF 1, Satoru Umegae DF 1, Takao Iwanaga DF 1, Ryutaro Nishikawa D 1, Takahiro Shimoyama DF 1, Sakurako Suzuki F 1, Shinichiro Atsumi CDF 3, Hiroshi Hasegawa F 2, Shigehito Nakashima DF 2, Kunihiro Higuchi F 2, Kentaro Onishi F 2, Ryotaro Sakaguchi F 2, Shoichi Morita F 2, Haruka Miyao F 2, Saki Aota F 2, Hikaru Ohtani F 1, Takayuki Yamamoto ADF 1
DOI: 10.12659/AJCR.948500
Am J Case Rep 2025; 26:e948500
Figure 5 Dynamic CT findings 18 days after the initial diagnosisDynamic CT images are shown in the plain phase (A), arterial phase (B), portal phase (C), and equilibrium/transitional phase (D). The hepatic tumor (yellow arrows) had enlarged to 75 mm (A–C), with tumor thromboses clearly observed in the right HV (C, blue arrow) and the anterior branch of the PV (C, purple arrow). Dynamic CT did not show early wash-in or wash-out in the hepatic tumor (yellow arrows). Additionally, a new solitary and swollen lymph node was detected dorsal to the PV trunk (D, pink arrow). CT – computed tomography; HV – hepatic vein; PV – portal vein.