25 August 2025
: Case report 
Rapid Progression of Primary Hepatic Neuroendocrine Carcinoma: A Case Report Demonstrating Drastic Oncological Behavior
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Rare disease, Adverse events of drug therapy
Rina Kobayashi BF 1, Tomohide Hori
ABCDEF 1*, Makoto Yamawaki CDF 2, Shigeki Nakayama DF 1, Satoru Umegae DF 1, Takao Iwanaga DF 1, Ryutaro Nishikawa D 1, Takahiro Shimoyama DF 1, Sakurako Suzuki F 1, Shinichiro Atsumi CDF 3, Hiroshi Hasegawa F 2, Shigehito Nakashima DF 2, Kunihiro Higuchi F 2, Kentaro Onishi F 2, Ryotaro Sakaguchi F 2, Shoichi Morita F 2, Haruka Miyao F 2, Saki Aota F 2, Hikaru Ohtani F 1, Takayuki Yamamoto ADF 1
DOI: 10.12659/AJCR.948500
Am J Case Rep 2025; 26:e948500
Figure 6 PET/CT findings 39 days after the initial diagnosisThe enlarged primary tumor in the liver (yellow arrows) exhibited a strong uptake value. Additionally, the swollen lymph node located dorsal to the PV trunk (pink arrows) also showed strong uptake. New, massively swollen lymph nodes with high uptake were detected around the pancreas head, inferior vena cava, and abdominal aorta (orange arrows). Simultaneously, a solitary but swollen cervical lymph node, measuring 20 mm (brown arrows), also emerged with strong uptake. HV – hepatic vein; PET/CT – positron emission-based tomography/computed tomography; PV – portal vein.