28 August 2025
: Case report 
Pancreatic Inflammation Induced by Immune Checkpoint Inhibitors in Melanoma Treatment: A Case Report
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy
Abdo I. El Tawil ABCDEF 1*, Beatriz A. Mendes ABCDEF 1, Leandro A.F. Machoski ABCDEF 1, Micheli F. Domingos AEF 2, Noelle S. Wassano AEF 3, Sérgio O. Ioshii AEF 4, Eduardo J.B. Ramos AEF 2DOI: 10.12659/AJCR.948580
Am J Case Rep 2025; 26:e948580
Figure 4 Histological section of pancreatic tissue obtained via endoscopic ultrasound-guided biopsy (H&E staining, high magnification) shows a dense inflammatory infiltrate composed predominantly of plasma cells (yellow arrows) and mature lymphocytes (red arrow), consistent with chronic inflammation. The surrounding stroma exhibits fibrosis and architectural distortion, with no evidence of malignant cells of any kind.