12 October 2025
: Case report 
Spontaneous Pleural, Pericardial, and Intracranial Hemorrhages in a Patient with End-Stage Kidney Disease Receiving Apixaban: A Case Report
Unusual clinical course, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Adebola Oluwabusayo Adetiloye
EF 1*, Moustafa Ismail EF 1, Farhana K. Alladin EF 2, Olurotimi J. Badero EF 3
DOI: 10.12659/AJCR.948821
Am J Case Rep 2025; 26:e948821
Figure 2 Transthoracic echocardiogram shows a moderate-to-large circumferential pericardial effusion measuring approximately 1.87 cm in diastole (blue caliper) and 1.87 cm posteriorly (yellow caliper). The effusion appears echo-dense with heterogeneous internal echoes, consistent with hemorrhagic or complex fluid rather than a simple serous effusion, as illustrated in the parasternal long-axis view (A), apical four-chamber view (B), and subcostal view (C), with the effusion highlighted by red arrows in each image.