12 October 2025
: Case report 
Spontaneous Pleural, Pericardial, and Intracranial Hemorrhages in a Patient with End-Stage Kidney Disease Receiving Apixaban: A Case Report
Unusual clinical course, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Adebola Oluwabusayo Adetiloye
EF 1*, Moustafa Ismail EF 1, Farhana K. Alladin EF 2, Olurotimi J. Badero EF 3
DOI: 10.12659/AJCR.948821
Am J Case Rep 2025; 26:e948821
Figure 3 Contrast-enhanced axial chest CT shows bilateral pleural effusions (orange arrows) with high attenuation, consistent with hemorrhagic effusions (A). The density (Hounsfield units) is higher than simple fluid, supporting the presence of blood within the pleural spaces. Contrast-enhanced sagittal chest CT demonstrates a large pericardial effusion (blue arrow) with increased attenuation, indicating a hemorrhagic pericardial effusion. This effusion surrounds the heart and is of higher density than simple serous fluid, consistent with blood (B).