30 September 2025
: Case report 
Severe Liver Dysfunction Within 48 Hours of Thionamide Therapy in Thyrotoxicosis: A Case Report
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment
Christopher Annabi ABCDEF 1, Laila Noor ABCDEF 2, Jamie A. Mullally
ABCDEF 2*
DOI: 10.12659/AJCR.948822
Am J Case Rep 2025; 26:e948822
Figure 2 Thyroid hormone levels are shown. (A) Free thyroxine levels steadily decreased within the normal range over the first 2.5 weeks and then subsequently trended upward until a total thyroidectomy on hospital day 23, after which levels decreased. (B) Total T3 (triiodothyronine) levels remained stable over the first 2.5 weeks and then trended upward before total thyroidectomy on hospital day 23, after which levels decreased.