Negative Anion Gap in Critically Ill Patients: A Case Study of Metabolic Alkalosis and Clinical Strategies

Xiuli Zou; Zhipeng Xie; Jiming Li

doi:10.12659/AJCR.948846

30 January 2026 : Case report China

Negative Anion Gap in Critically Ill Patients: A Case Study of Metabolic Alkalosis and Clinical Strategies

Unusual clinical course, Challenging differential diagnosis, Unexpected drug reaction, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology

Xiuli Zou^{AFG 1*}, Zhipeng Xie^{AEF 2}, Jiming Li^{BD 3}

DOI: 10.12659/AJCR.948846

Am J Case Rep 2026; 27:e948846

Authors information Article notes Copyright and License information

Introduction Case Report Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Figure 2 Trends of blood gas Indicators. PH – pH; ACAG – albumin-corrected anion gap; HCO3− – bicarbonate ion; SID – strong anion difference.

Back to the Article

Negative Anion Gap in Critically Ill Patients: A Case Study of Metabolic Alkalosis and Clinical Strategies

Your Privacy