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13 September 2025 : Case report  China

Giant Intra-Abdominal Tumor, Compatible with Liposarcoma: A Case Report and Literature Review

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology

Niu Dai ORCID logo AEF 1,2, Juzheng Yuan AEF 1, Xiaoyi Wang B 1, He Bai E 1, Haohao Ding B 1, Xiao Li FG 1*, Shuqiang Yue EFG 1

DOI: 10.12659/AJCR.948952

Am J Case Rep 2025; 26:e948952

Figure 3 Pathological results(A) H&E staining, Tumor invasion of the kidney and necrosis in the kidney. (HE). The tumor cells were sparsely arranged and some were fusiform. (B) FISH showed the MDM2 gene was amplified, but DDIT3 was not. (C) IHC staining, CDK4 (+), MDM2 (+) were identified as WD/DDLPS, CD56 (+), Ki-67 (10–30%). Arrows indicate positive.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923